CES 2026: PreEvnt Isaac Non-Invasive Glucose Monitor Ends the Needle Prick

The holy grail of the wearables industry—tracking blood sugar without needles—has finally arrived at CES 2026. While tech giants like Apple have spent millions chasing optical sensors, a startup named PreEvnt has unveiled Isaac, a device that monitors glucose levels simply by analyzing a user's breath.

How the PreEvnt Isaac Non-Invasive Glucose Monitor Works

Instead of trying to look through the skin, Isaac measures volatile organic compounds (VOCs) in the breath. It specifically looks for acetone, a biomarker that correlates with blood sugar spikes. The device is roughly the size of a quarter and can be worn around the neck or carried in a bag, making it significantly less intrusive than traditional continuous glucose monitors (CGMs).

When a user breathes onto the disc, the data is computed and logged into a companion smartphone app. Although the price is TBD, the value it provides to those who dread daily pinpricks is immeasurable. The app even includes emergency contact features for when a user becomes incapacitated due to hypoglycemia.

Clinical Trials and Path to FDA Authorization

According to Adrienne So, Isaac entered active human clinical trials at Indiana University in late 2025. The study compares the device's accuracy against traditional methods, starting with adolescents with Type 1 diabetes. PreEvnt is currently working with the FDA via a de novo application, aiming for market authorization in 2026.